Mkrtchyan, SatenikJakubczyk, MichałSarfaraz, SehrishAyub, KhurshidIaroshenko, Viktor O.2025-07-042025-07-0420242041-65202041-6539https://doi.org/10.1039/D4SC01704Hhttps://repo.umb.sk/handle/123456789/729In: Chemical Science. Cambridge : Royal Society of Chemistry, 2024. ISSN 2041-6520. Vol. 15, no. 36 (2024), pp. 14798-14805.Activation of phenols by a Ru-catalyst allows for the resulting η5-phenoxo complex to selectively react with a variety of nucleophiles under mechanochemical conditions. Conversion of phenolic hydroxy groups without derivatization is important for late-stage modifications of pharmaceuticals and in the context of lignin-material processing. We present a one-step, Ru-catalyzed cross-coupling of phenols with boronic acids, aryl trialkoxysilanes and potassium benzoyltrifluoroborates under mechano-chemical conditions. The protocol accepts a wide scope of starting materials and allows for gram-scale synthesis in excellent yields. The developed approach constitutes a very interesting and waste-limiting alternative to the known methods.enCC BY Creative Commons Attribution 4.0. Internationalinfo:eu-repo/semantics/openAccessmechanochémiamechanochemistryfenolychémiachemistrykatalyzátoryArticle